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KMID : 0366119730010010019
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Korean Journal of Applied Microbiology & Bioengineering
1973 Volume.1 No. 1 p.19 ~ p.22
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The Effect of Penicillin on the growth of Bacillus subtilis
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Abstract
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This experiment was done to investigate the growth and the fine structural changes of Bacillus subtilis which were influenced by the penicillin with electromicroscope. The results were as follows;
1) The higher the concentration of penicillin the more prominent inbilition of the growth was observed.
2) The septa was not formed, derangements of synthesis of cell wall and cell membrane.
3) Cytoplasm was increased with swelling of cell body because of weakness of cell membrane induced by deranged synthesis of cell membrane. Some of the cells showed desruption of their membrane with loss of cytoplasm, remaining empty space, which suggest. loss of cell function.
4) It can be suggested that penicillin had affected on the cell wall of Bacillus subtilis, and inhibited growth of the cell by deranging the formation of the cell wall.
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